Board of Directors

  • Dr. Neal Walker

    Chair

    Dr. Walker co-founded Aclaris and has served as Chair of Aclaris’ board of directors since January 2023. Dr. Walker previously served as Aclaris’ Chief Executive Officer and has served as a member of the board of directors since its inception in July 2012. He is a board-certified dermatologist and serial entrepreneur with over 20 years of experience in the life science industry. He began his pharmaceutical industry career at Johnson & Johnson. Dr. Walker co-founded NeXeption, LLC, a biopharmaceutical assets management company, in 2012, and its affiliated companies. Prior to Aclaris, he co-founded and served as President and Chief Executive Officer and a member of the board of directors of Vicept Therapeutics, Inc., a dermatology-focused specialty pharmaceutical company, from 2009 until its acquisition by Allergan, Inc. in 2011. Previously, Dr. Walker co-founded and led a number of life science companies, including Octagon Research Solutions, Inc., a software and services provider to biopharmaceutical companies (acquired by Accenture plc); Trigenesis Therapeutics, Inc., a specialty dermatology company, where he served as Chief Medical Officer (acquired by Dr. Reddy's Laboratories Inc.); and Cutix Inc., a commercial dermatology company. He also co-founded and previously served on the boards of the Dermatology Summit, Dermatology Innovation Forum, and Advancing Innovation in Dermatology. Dr. Walker is on the board of directors of Aldeyra Therapeutics, Inc., a publicly held biotechnology company, as well as several private companies. In 2016, Dr. Walker was awarded the Frank Baldino Bioscience CEO of the Year award and the Ernst & Young Entrepreneur of the Year Greater Philadelphia award. He is a Fellow of the American Academy of Dermatology. He received a Master of Business Administration from The Wharton School of the University of Pennsylvania, a Doctor of Osteopathic Medicine from the Philadelphia College of Osteopathic Medicine, and a Bachelor of Arts in biology from Lehigh University.

  • Christopher Molineaux

    Lead Independent Director

    Christopher Molineaux has served as Lead Independent Director of Aclaris’ board of directors since January 2023, having previously served as Chairman since June 2019. He has been a member of Aclaris’ board of directors since January 2014. Mr. Molineaux is President and Chief Executive Officer of Life Sciences Pennsylvania, formerly Pennsylvania Bio, a pharmaceutical and biotech industry advocacy organization. Before joining Life Sciences Pennsylvania in 2009, Mr. Molineaux served as worldwide Vice President of Pharmaceutical Communications and Public Affairs for Johnson & Johnson. Mr. Molineaux previously served as Vice President for Public Affairs at the Pharmaceutical Research and Manufacturers of America (PhRMA) and held positions at the Federal Department of Health & Human Services and the White House. He received a Bachelor of Arts from the College of the Holy Cross.

  • Maxine Gowen, Ph.D.

    Director

    Maxine Gowen has served as a member of Aclaris’ board of directors since July 2019. Dr. Gowen joined TamuroBio Inc., a biotechnology company, in August 2019, and served as its part-time Chief Executive Officer until December 2021.  Dr. Gowen founded Trevena, Inc., a publicly held biopharmaceutical company, and served as its President and Chief Executive Officer from 2007 until October 2018. Prior to this, Dr. Gowen held a variety of leadership roles at GlaxoSmithKline (GSK) over a period of fifteen years. As Senior Vice President for the Center of Excellence for External Drug Discovery (CEEDD), she developed an innovative new approach to externalizing drug discovery in big pharma. Dr. Gowen was previously President and Managing Partner at SR One, the venture capital subsidiary of GSK, where she led its investments in, and served on the board of directors of, numerous companies. Until 2002, Dr. Gowen was Vice President, Drug Discovery, Musculoskeletal Diseases at GSK, responsible for drug discovery and early development for osteoporosis, arthritis and metastatic bone disease. Dr. Gowen held a tenured academic position in the School of Pharmacology, University of Bath, UK from 1989 to 1992. Dr. Gowen currently serves on the boards of directors of the publicly held companies Aceragen, Inc. (f/k/a Idera Pharmaceuticals, Inc.), Merus N.V. and Passage Bio, Inc. Dr. Gowen previously served on the boards of directors of the publicly held companies Trevena, Inc. and Akebia Therapeutics, Inc. Dr. Gowen served on the board of the national biotechnology industry association, BIO, from 2008 to 2018. Dr. Gowen received a Bachelor of Science in biochemistry from the University of Bristol, UK, then received a Doctor of Philosophy in cell biology from the University of Sheffield, UK, and received a Master of Business Administration from The Wharton School of the University of Pennsylvania. Dr. Gowen also received a Doctor of Science by the University of Bath, UK.

  • William Humphries

    Director

    William D. Humphries has served as a member of Aclaris’ board of directors since September 2016. Mr. Humphries joined Isosceles Pharmaceuticals Inc., a biotechnology company, in May 2021 and serves as its Chief Executive Officer. From August 2018 to December 2020, Mr. Humphries served as President of Ortho Dermatologics, the dermatology division of Bausch Health Companies, Inc., and previously served as its Executive Vice President, Company Group Chairman for Dermatology and OraPharma. Previously, he served as President and Chief Executive Officer of the North American business of Merz, Inc., an affiliate of Merz Pharma Group, where he oversaw strategic direction and collaboration among three North American companies: Merz Pharmaceuticals LLC, Merz Aesthetics Inc., and Merz Pharma Canada Ltd. Before joining Merz, he served in a number of leadership positions with Stiefel Laboratories, Inc., including as its Chief Commercial Officer and then as President, where he spearheaded two significant acquisitions and led the global integration of Stiefel into GlaxoSmithKline. Previously, Mr. Humphries held multiple senior executive roles in sales and marketing, business development and international marketing for Allergan, Inc., concluding as Vice President of its U.S. skincare business. He currently serves as chairman of the boards of directors of Clearside Biomedical, Inc., a publicly held biopharmaceutical company, and STRATA Skin Sciences, Inc., a publicly held medical technology company, as a director of the publicly held company PhaseBio Pharmaceuticals, Inc. and as a director of Bryn Pharmaceuticals and SKNY, both privately held life science companies. He received a Bachelor of Arts from Bucknell University and a Master of Business Administration from Pepperdine University.

  • Douglas Manion, M.D., FRCP (C)

    Director, Chief Executive Officer and President

    Douglas Manion, MD, FRCP (C), has served as Aclaris' Chief Executive Officer and President, and as a director, since January 2023. He joined Aclaris in August 2022 as President and Chief Operating Officer. Dr. Manion brings over 25 years of pharmaceutical industry experience in both large and small companies. 

    Prior to joining Aclaris, Dr. Manion served as Executive Vice President of Research & Development of Arena Pharmaceuticals, Inc., a biopharmaceutical company, from July 2021 until its acquisition by Pfizer Inc. in March 2022. Dr. Manion previously served as Chief Executive Officer of Global BioShield, a not-for-profit company developing immunotherapies for COVID, from January to July 2021. He also served as Chief Executive Officer of Kleo Pharmaceuticals, Inc., an immuno-oncology company, from May 2017 until its acquisition by Biohaven Pharmaceutical Holding Company Ltd. in January 2021. Between 2005 and 2016, Dr. Manion served in roles of increasing responsibility at Bristol-Myers Squibb, or BMS, mostly recently as Senior Vice President, Head of Specialty Development and Head of R&D China and Japan. During his tenure at BMS, he held leadership roles overseeing global clinical research, clinical development, pharmacovigilance and biostatistics across various therapeutic areas, including virology, immunology, neurology, cardiology, metabolic diseases, genetically-defined diseases and fibrosis. Dr. Manion’s previous biopharmaceutical experience included leadership roles at GlaxoSmithKline, DuPont Pharmaceuticals and DuPont Merck Pharmaceuticals. 

    Dr. Manion received a B.A.Sc in Civil Engineering followed by an M.D. from the University of Ottawa in Canada. He is Board Certified in Internal Medicine, completed an Infectious Diseases Clinical Fellowship from the University of Ottawa and completed a post-doctoral research fellowship at Massachusetts General Hospital and Harvard Medical School. Dr. Manion serves on the board of directors of the private biopharmaceutical company Lakewood-Amedex, Inc.

  • Anand Mehra, M.D.

    Director

    Dr. Mehra has served as a member of Aclaris’ board of directors since September 2014. Dr. Mehra joined Sofinnova Investments, Inc. (fka Sofinnova Ventures, Inc.), a biotech investment firm, in 2007 and served as a Managing General Partner until January 2020. Prior to joining Sofinnova, Dr. Mehra worked in J.P. Morgan's private equity and venture capital group, and before that, Dr. Mehra was a consultant in McKinsey & Company's pharmaceutical practice. Dr. Mehra currently serves as the chairman of the board of directors of the publicly held company Merus N.V. He previously served on the board of directors of the pharmaceutical company Spark Therapeutics, Inc. Dr. Mehra received his Bachelor of Arts in political philosophy from the University of Virginia and a Doctor of Medicine from Columbia University's College of Physicians and Surgeons.

  • Vincent Milano

    Director

    Vincent Milano has served as a member of Aclaris’ board of directors since January 2020. Mr. Milano was appointed chair of the board of Aceragen Inc. (f/k/a Idera Pharmaceuticals, Inc.) a publicly held biopharmaceutical company, in 2022, having previously served as Idera's President and CEO and a member of Idera's board of directors since 2014. Prior to joining Idera, from 1996 to 2014, Mr. Milano served in increasingly senior roles at ViroPharma Inc., a pharmaceutical company acquired by Shire plc in 2014, most recently as Chairman, President and Chief Executive Officer from 2008 to 2014. Prior to joining ViroPharma, Mr. Milano served in increasingly senior roles, most recently as a senior manager, at KPMG LLP, an independent registered public accounting firm, from 1985 to 1996. Mr. Milano also previously served on the boards of directors of the publicly held companies Spark Therapeutics, Inc. and Vanda Pharmaceuticals Inc., and VenatoRx Pharmaceuticals, Inc. a privately held company. Mr. Milano currently serves on the boards of directors of BioCryst Pharmaceuticals, Inc., a publicly held company, and Life Sciences Cares Philadelphia, a non-profit organization. Mr. Milano received a Bachelor of Science in Accounting from Rider College.

  • Andrew Powell, Esq.

    Director

    Andrew Powell is an independent consultant who has served as a member of Aclaris’ board of directors since January 2017. Mr. Powell served as Senior Vice President, General Counsel and Corporate Secretary of Medivation, Inc. from 2015 through the company’s acquisition by Pfizer, Inc. in 2016. Prior to Medivation, Mr. Powell served as Executive Vice President, General Counsel and Corporate Secretary of InterMune, Inc. from 2013 to 2015, where he helped the company prepare for the U.S. approval and launch of Esbriet® (pirfenidone) as a treatment for idiopathic pulmonary fibrosis and played a leadership role in InterMune’s acquisition by Swiss drug maker Roche Holdings AG. Immediately prior to joining InterMune, he was Executive Vice President, General Counsel and Secretary at Cornerstone Therapeutics, Inc. through its successful sale to Chiesi Farmaceutici S.p.A. Prior to Cornerstone, Mr. Powell served as Senior Vice President and General Counsel at ImClone Systems, Inc. where he helped the company grow before playing a key role in a successful process that resulted in a sale to Eli Lilly and Company. Prior to ImClone Systems, he was part of the senior team that repositioned CollaGenex Pharmaceuticals, Inc. as a leader in dermatology. Early in his career, Mr. Powell held positions of increasing responsibility for nearly 15 years at the multinational health care company Baxter International, Inc., where he was instrumental in a series of transactions that established Baxter throughout Asia. Mr. Powell previously serves on the board of directors of Silverback Therapeutics, Inc., (now known as ARS Pharmaceuticals, Inc.) Landee Corporation (now known as Lifecore Biomedical, Inc.), Synthorx Inc., a biopharmaceutical company acquired by Sanofi Aventis in January 2020, and Motif Bio plc. Mr. Powell received a Bachelor of Arts from the University of North Carolina at Chapel Hill and a Juris Doctorate from Stanford Law School.

  • Bryan Reasons

    Director

    Bryan Reasons has served as a member of Aclaris’ board of directors since April 2018. Mr. Reasons is the Executive Vice President and Chief Financial Officer of Mallinckrodt plc.  Prior to joining Mallinckrodt, Mr. Reasons served as the Chief Financial Officer of Amneal Pharmaceuticals, Inc. and prior to that as Senior Vice President, Finance and Chief Financial Officer of Impax Laboratories, Inc. until its acquisition by Amneal in 2018. Before joining Impax, he was Vice President, Finance of Cephalon, Inc. and of Teva Pharmaceutical Industries Ltd., following the acquisition of Cephalon by Teva. Mr. Reasons previously worked at E.I. du Pont de Nemours and Company and PricewaterhouseCoopers LLP. Mr. Reasons currently serves on the board of directors and on the audit committee of Societal CMDO (f/k/a Recro Pharma, Inc.), a publicly held company. Mr. Reasons received a Bachelor of Science in accounting from The Pennsylvania State University and a Master of Business Administration from Widener University. He is a certified public accountant in the Commonwealth of Pennsylvania.

  • Andrew Schiff, M.D.

    Director

    Dr. Schiff has served as a member of Aclaris’ board of directors since August 2017. Dr. Schiff joined Aisling Capital, an investment firm, in 1999 and currently serves as one of its managing partners. Prior to joining Aisling Capital, Dr. Schiff practiced internal medicine for six years at The New York Presbyterian Hospital, where he maintains his position as a Clinical Assistant Professor of Medicine. Dr. Schiff currently serves on the board of directors of the publicly held company Monte Rosa Therapeutics, Inc. Dr. Schiff also currently serves on the board of directors at the privately held company Dren Bio. He previously served as a director of the life sciences company ZELTIQ Aesthetics, Inc. He is a longtime supporter and board member of the Visiting Nurse Service of New York, as well as other charitable organizations. Dr. Schiff received a Doctor of Medicine from Cornell University Medical College, a Master of Business Administration from Columbia University, and a Bachelor of Science, with honors in neuroscience, from Brown University.